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Longev 2016:3286365

Genetic Predispositions and Why One-Size-Fits-All OTC Approaches Miss the Mark Variants in genes controlling GLP-1 receptor function insulin secretion pathways (GIPR rs1800437), and appetite regulation (MC4R rs17782313, FTO rs9939609) influence how individuals respond to weight-loss interventions

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This may require longer and more extensive clinical development, or regulatory authorities may increase the amount of data and information required to approve, market or maintain approval for azelaprag or any future product candidates and could result in warnings and precautions in our product labeling or a restrictive REMS

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